It's all about the belly cut
A big reason why the Stratocaster (HH model shown above) is such a comfortable player is because of its contour cut in the rear of the body, known commonly as the belly cut.
It can arguably be said that the best music is the kind that takes you to another place when you listen to it. For a song to do that, it has to be crafted in such a way that gives it a bit of a magical other-worldly feeling. Put simply, "make it big."
Fun fact: Most super-big musical instrument manufacturers are still run like mom-and-pop businesses.